PKA C (pan) Antibody (485013) [DyLight 350]
Novus Biologicals, part of Bio-Techne | Catalog # FAB4175D
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human, Mouse, Rat
Applications
Western Blot
Label
DyLight 350 (Excitation = 353 nm, Emission = 432 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # 485013
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant human PKA C gamma
Met1-Phe351
Accession # ABM84853
Met1-Phe351
Accession # ABM84853
Specificity
Detects human PKA C alpha, C beta, and C gamma as well as endogenous human, mouse, and rat PKA C isoforms at 39-42 kDa using Western blot.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Applications for PKA C (pan) Antibody (485013) [DyLight 350]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: PKA C (pan)
The cAMP-dependent protein kinase (PKA) holoenzyme is composed of two regulatory and two catalytic subunits, designated PKA R and PKA C, respectively. Upon PKA R subunit binding to the second messenger cAMP, active PKA C subunits are released, initiating a phosphorylation cascade that regulates such cellular functions as metabolism, ion transport, and gene transcription. Catalytic PKA subunit isoforms, Cα, Cβ and, in humans, Cγ, have been identified.
Long Name
cAMP-dependent Protein Kinase Catalytic Subunit
Alternate Names
CAFD1, PKACA, PPNAD4
Additional PKA C (pan) Products
Product Documents for PKA C (pan) Antibody (485013) [DyLight 350]
Product Specific Notices for PKA C (pan) Antibody (485013) [DyLight 350]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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