PA1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76239

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NBP1-76239
NBP1-76239-0.025mg
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Conjugate
Catalog #
Alexa Fluor 350
NBP1-76239AF350
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Alexa Fluor 405
NBP1-76239AF405
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Alexa Fluor 488
NBP1-76239AF488
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Alexa Fluor 532
NBP1-76239AF532
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Alexa Fluor 594
NBP1-76239AF594
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Alexa Fluor 647
NBP1-76239AF647
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Alexa Fluor 700
NBP1-76239AF700
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Alexa Fluor 750
NBP1-76239AF750
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Alexa Fluor Plus 405
NBP1-76239AFP405
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Alexa Fluor Plus 488
NBP1-76239AFP488
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Alexa Fluor Plus 555
NBP1-76239AFP555
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Alexa Fluor Plus 594
NBP1-76239AFP594
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Alexa Fluor Plus 647
NBP1-76239AFP647
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Alexa Fluor Plus 680
NBP1-76239AFP680
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Allophycocyanin
NBP1-76239APC
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Biotin
NBP1-76239B
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CoraFluor 1
NBP1-76239CL1
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DyLight 350
NBP1-76239UV
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DyLight 405
NBP1-76239V
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DyLight 488
NBP1-76239G
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DyLight 550
NBP1-76239R
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DyLight 594
NBP1-76239DL594
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DyLight 650
NBP1-76239C
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DyLight 680
NBP1-76239FR
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DyLight 755
NBP1-76239IR
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FITC
NBP1-76239F
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HRP
NBP1-76239H
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Janelia Fluor 525
NBP1-76239JF525
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Janelia Fluor 549
NBP1-76239JF549
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Janelia Fluor 646
NBP1-76239JF646
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Janelia Fluor 669
NBP1-76239JF669
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mFluor Violet 450 SE
NBP1-76239MFV450
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mFluor Violet 500 SE
NBP1-76239MFV500
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mFluor Violet 610 SE
NBP1-76239MFV610
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PE
NBP1-76239PE
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PerCP
NBP1-76239PCP
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all PA1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human GAS. The immunogen is located within the last 50 amino acids of GAS.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PA1 Antibody - BSA Free

Western Blot: PA1 AntibodyBSA Free [NBP1-76239]

Western Blot: PA1 AntibodyBSA Free [NBP1-76239]

Western Blot: PA1 Antibody [NBP1-76239] - EL4 cell lysate in (A) the absence and (B) the presence of blocking peptide with PA1 antibody at 1ug/mL.

Applications for PA1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PA1

Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators, but they have recently been determined to co-regulate transcription initiated by other transcription factors. GAS is a recently identified glutamate-rich protein that interacts with SRC1, but not GRIP1 or AIB1, the other two members of the SRC family. GAS can also interact with the alpha subunit of the estrogen receptor (ERalpha), but not other receptors such as the retinoic acid receptor a, suggesting the interaction between GAS and ERalpha is relatively specific. Depletion of GAS by RNA interference in MCF7 cells led to a decrease in the mRNA and protein levels of ER target genes such as pS2, c-Myc and cyclin D1, indicating the role of GAS in the regulation of ER target genes. GAS has also been found to associate with an SET1-like methyltransferase complex specific for H3K4 methylation, suggesting that GAS has multiple roles in transcriptional regulation.

Alternate Names

chromosome 16 open reading frame 53, FLJ22459, GAS, glutamate-rich coactivator interacting with SRC1/NCOA1, MGC4606, PA1, PAXIP1-associated protein 1, PTIP-associated 1 protein, PTIP-associated protein 1

Gene Symbol

PAGR1

UniProt

NP_078792 (Human)

Additional PA1 Products

Product Documents for PA1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PA1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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