BCAR1/p130CAS functions as a scaffolding protein for components of various kinase signaling pathways. It is involved in integrin signaling for cell motility as well as netrin signaling for the guidance of commissural axons. Overexpression of BCAR1/p130CAS has been shown to confer antiestrogen resistance in breast cancer cells. Alternate names for BCAR1/p130CAS include breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, CAS scaffolding protein family member 1, CAS, and CRKAS.

Long Name

Breast Cancer Anti-estrogen Resistance 1

Alternate Names

BCAR1, CASS1, CRKAS

Gene Symbol

BCAR1

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Product Documents for p130Cas/BCAR1 Antibody [PE]

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Product Specific Notices for p130Cas/BCAR1 Antibody [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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p130Cas/BCAR1 Antibody [PE]

Novus Biologicals, part of Bio-Techne | Catalog # AF5730P

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Applications for p130Cas/BCAR1 Antibody [PE]

Western Blot

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Background: p130Cas