Orai1 Antibody - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85463
Key Product Details
Species Reactivity
Validated:
Human
Predicted:
Mouse (95%), Rat (95%). Backed by our 100% Guarantee.
Applications
Western Blot, Immunocytochemistry/ Immunofluorescence
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
BSA Free
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SLVSHKTDRQFQELNELAEFARLQDQLDHRGDHPLTPGSHYA
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for Orai1 Antibody - BSA Free
![Immunocytochemistry/ Immunofluorescence: Orai1 Antibody [NBP1-85463]](https://resources.bio-techne.com/images/products/Orai1-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-85463-img0012.jpg "Immunocytochemistry/ Immunofluorescence: Orai1 Antibody [NBP1-85463]")
Immunocytochemistry/ Immunofluorescence: Orai1 Antibody [NBP1-85463]
Immunocytochemistry/Immunofluorescence: Orai1 Antibody [NBP1-85463] - Staining of human cell line U-251 MG shows localization to cytosol. Antibody staining is shown in green.![Western Blot: Orai1 Antibody [NBP1-85463]](https://resources.bio-techne.com/images/products/Orai1-Antibody-Western-Blot-NBP1-85463-img0013.jpg "Western Blot: Orai1 Antibody [NBP1-85463]")
Western Blot: Orai1 Antibody [NBP1-85463]
Western Blot: Orai1 Antibody [NBP1-85463] - Analysis in human cell line NB4.Applications for Orai1 Antibody - BSA Free
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
0.25-2 ug/ml
Western Blot
0.04 - 0.4 ug/ml
Application Notes
IHC-Paraffin, HIER pH 6 retrieval method is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Orai1
Orai1 is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. Orai1 is a pore subunit of Ca(2+) release-activated Ca(2+) CRAC channels, and STIM1 acts as an endoplasmic reticulum (ER) Ca(2+) sensor that detects store depletion. This type of channel is the primary way for calcium influx into T-cells. Defects in Orai1 are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1.
Long Name
ORAI Calcium Release-activated Calcium Modulator 1
Alternate Names
CRACM1, ORAT1, TMEM142A
Gene Symbol
ORAI1
Additional Orai1 Products
Product Documents for Orai1 Antibody - BSA Free
Product Specific Notices for Orai1 Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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