Orai1 Antibody (8C0) - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-43010
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # 8C0
Format
BSA Free
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
ORAI calcium release-activated calcium modulator 1 - (Uniprot# Q96D31)
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Theoretical MW
32 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for Orai1 Antibody (8C0) - BSA Free
Immunohistochemistry: Orai1 Antibody (8C0) [NBP3-43010] -
Immunohistochemistry: Orai1 Antibody (8C0) [NBP3-43010] - Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using (Orai1 Antibody) at dilution of 1:200
Western Blot: Orai1 Antibody (8C0) [NBP3-43010] -
Western Blot: Orai1 Antibody (8C0) [NBP3-43010] - HL-60 cells were subjected to SDS PAGE followed by western blot with (Orai1 Antibody) at dilution of 1:1000Applications for Orai1 Antibody (8C0) - BSA Free
Application
Recommended Usage
Immunohistochemistry
1:50 - 1:500
Western Blot
1:500 - 1:2000
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
PBS (pH 7.3), 50% glycerol
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C. Avoid freeze-thaw cycles.
Background: Orai1
Orai1 is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. Orai1 is a pore subunit of Ca(2+) release-activated Ca(2+) CRAC channels, and STIM1 acts as an endoplasmic reticulum (ER) Ca(2+) sensor that detects store depletion. This type of channel is the primary way for calcium influx into T-cells. Defects in Orai1 are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1.
Long Name
ORAI Calcium Release-activated Calcium Modulator 1
Alternate Names
CRACM1, ORAT1, TMEM142A
Gene Symbol
ORAI1
Additional Orai1 Products
Product Documents for Orai1 Antibody (8C0) - BSA Free
Product Specific Notices for Orai1 Antibody (8C0) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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