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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

Product Summary for NUMBL Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 200 and 250 of human numb (Drosophila) homolog-like using the numbering given in entry NP_004747.1 (GeneID 9253).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NUMBL Antibody

Immunoprecipitation: NUMBL Antibody [NB100-88136] - Detection of Human NUMBL1 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-NUMBL1 antibody Nb100-88136 used for IP at 3 mcg/mg lysate. NUMBL1 was also immunoprecipitated by rabbit anti-NUMBL1 antibody NB100-88137, which recognizes a downstream epitope. Detection: Chemiluminescence with an exposure time of 3 seconds.

Applications for NUMBL Antibody

Application
Recommended Usage

Immunoprecipitation

2 - 5 ug/mg lysate
Application Notes
This antibody is not recommended for Western Blot analysis.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: NUMBL

NUMBL [numb (drosophila) homolog-like] is functionally related to NUMB, a protein that plays an essential role in the determination of cell fate for sensory organ and neural development. Polyglutamine repeats in the NUMBL gene have been associated with schizophrenia in two unrelated populations. Alternate names for NUMBL include NBL, CAG3A, CTG3a, NUMBR, TNRC23, and NUMBLIKE.

Alternate Names

CAG3A, CTG3a, numb (Drosophila) homolog-like, numb homolog (Drosophila)-like, numb homolog-like, NUMBLIKE, numb-like protein, Numb-R, Numb-related protein, NUMBRNBL, TNRC23

Entrez Gene IDs

9253 (Human)

Gene Symbol

NUMBL

Product Documents for NUMBL Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NUMBL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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