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NMDAR2B Antibody (17) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-43543

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-43543

Key Product Details

Species Reactivity

Rat

Applications

X-Ray Crystallography

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 Clone # 17

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Monoclonal antibodies that bind rat GluN2B ATD were obtained by immunizing mice with the purified intact GluN1-GluN2B NMDA receptors. IgGs were purified from hybridoma cell culture supernatant by Protein-A Sepharose. Fab fragments have been prepared by papain proteolysis followed by re-chromatographing onto Protein-A Sepharose to remove Fc. (Uniprot# Q00960)

Specificity

Reacts specifically with rat GluN2B ATD.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Novus Biologicals Mouse NMDAR2B Antibody (17) - BSA Free (NBP3-43487) is a recombinant monoclonal antibody validated for use in X-Ray Crystallography. All Novus Biologicals antibodies are covered by our 100% guarantee.

Applications for NMDAR2B Antibody (17) - BSA Free

Application
Recommended Usage

X-Ray Crystallography

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NMDAR2B

NMDA receptor 2B is an ion channels activated by glutamate. NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are also implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors like NMDAR2B also appear to be a target for ethanol at physiological concentrations and therefore may play a significant role in alcoholism.

Alternate Names

glutamate [NMDA] receptor subunit epsilon-2, glutamate receptor subunit epsilon-2, glutamate receptor, ionotropic, N-methyl D-aspartate 2B, hNR3, MGC142180, NMDAR2BMGC142178, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NR2B, NR3

Gene Symbol

GRIN2B

Additional NMDAR2B Products

Product Documents for NMDAR2B Antibody (17) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NMDAR2B Antibody (17) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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