NLRP1/NALP1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76656

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NBP1-76656
NBP1-76656-0.025mg
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Conjugate
Catalog #
Alexa Fluor 350
NBP1-76656AF350
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Alexa Fluor 405
NBP1-76656AF405
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Alexa Fluor 488
NBP1-76656AF488
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Alexa Fluor 532
NBP1-76656AF532
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Alexa Fluor 594
NBP1-76656AF594
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Alexa Fluor 647
NBP1-76656AF647
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Alexa Fluor 700
NBP1-76656AF700
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Alexa Fluor 750
NBP1-76656AF750
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Alexa Fluor Plus 405
NBP1-76656AFP405
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Alexa Fluor Plus 488
NBP1-76656AFP488
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Alexa Fluor Plus 555
NBP1-76656AFP555
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Alexa Fluor Plus 594
NBP1-76656AFP594
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Alexa Fluor Plus 647
NBP1-76656AFP647
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Alexa Fluor Plus 680
NBP1-76656AFP680
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Allophycocyanin
NBP1-76656APC
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Biotin
NBP1-76656B
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CoraFluor 1
NBP1-76656CL1
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DyLight 350
NBP1-76656UV
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DyLight 405
NBP1-76656V
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DyLight 488
NBP1-76656G
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DyLight 550
NBP1-76656R
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DyLight 594
NBP1-76656DL594
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DyLight 650
NBP1-76656C
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DyLight 680
NBP1-76656FR
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DyLight 755
NBP1-76656IR
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FITC
NBP1-76656F
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HRP
NBP1-76656H
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Janelia Fluor 525
NBP1-76656JF525
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Janelia Fluor 549
NBP1-76656JF549
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Janelia Fluor 646
NBP1-76656JF646
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Janelia Fluor 669
NBP1-76656JF669
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mFluor Violet 450 SE
NBP1-76656MFV450
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mFluor Violet 500 SE
NBP1-76656MFV500
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mFluor Violet 610 SE
NBP1-76656MFV610
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PE
NBP1-76656PE
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PerCP
NBP1-76656PCP
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all NLRP1/NALP1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to 13 amino acids near the carboxy terminus of human NALP1. The immunogen is located within the last 50 amino acids of NALP1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NLRP1/NALP1 Antibody - BSA Free

Western Blot: NLRP1/NALP1 AntibodyBSA Free [NBP1-76656]

Western Blot: NLRP1/NALP1 AntibodyBSA Free [NBP1-76656]

Western Blot: NLRP1/NALP1 Antibody [NBP1-76656] - U937 cell lysate with NALP1 antibody at (A) 1, (B) 2 and (C) 4 ug/ml.
NLRP1/NALP1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: NLRP1/NALP1 Antibody - BSA Free [NBP1-76656] -

Immunocytochemistry/ Immunofluorescence: NLRP1/NALP1 Antibody - BSA Free [NBP1-76656] - Immunofluorescence of NLRP1/NALP1 in K562 cells with NLRP1/NALP1 antibody at 20 ug/mL.
NLRP1/NALP1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: NLRP1/NALP1 Antibody - BSA Free [NBP1-76656] -

Immunocytochemistry/ Immunofluorescence: NLRP1/NALP1 Antibody - BSA Free [NBP1-76656] - Immunocytochemistry of NLRP1/NALP1 in K562 cells with NLRP1/NALP1 antibody at 10 ug/mL.

Applications for NLRP1/NALP1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

10-20 ug/mL

Western Blot

1-4 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NLRP1/NALP1

NALP1 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. It contains a caspase recruitment domain (CARD) in addition to a NACHT domain and leucine rich repeat (LRR). This protein interacts strongly with caspase 2 and weakly with caspase 9, as well as with Apaf-1. Transient overexpression of this gene in cultured cells was sufficient to induce apoptosis. NALP1 mRNA and protein expression levels in myeloid leukemia cells are increased following CREB (cAMP-response element binding protein) activation, suggesting that NALP1 may contribute to modulate the response of these cells to pro-inflammatory stimuli. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for NALP1.

Long Name

NLR Family, Pyrin Domain Containing 1

Alternate Names

CARD7, CLR17.1, DEFCAP, NALP1, PP1044, SLEV1, VAMAS1

Gene Symbol

NLRP1

UniProt

AAG30288 (Human)

Additional NLRP1/NALP1 Products

Product Documents for NLRP1/NALP1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for NLRP1/NALP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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