Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Polyclonal Goat IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Neuregulin-1 beta 1/NRG1 beta 1 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human NRG1-beta 1/HRG1-beta 1
Ser2-Lys246
Accession # AAA58639

Specificity

Detects human NRG1-beta 1/HRG1-beta 1 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross‑reactivity with the EGF domain of recombinant human (rh) NRG1-beta 1/HRG1-beta 1 is observed and less than 1% cross-reactivity with rhNRG-2 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Neuregulin-1 beta 1/NRG1 beta 1 Antibody [PE]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Neuregulin-1 beta 1/NRG1 beta 1

The neuregulin (also known as heregulin) cytokine family is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. The NRG1 gene is the most pleiotropic, encoding more than 14 soluble or transmembrane proteins. NRG1 isoforms can be classified into type I (neu differentiation factor, NDF; heregulin, HRG; acetylcholine receptor inducing activity, ARIA), type II (glial growth factor, GGF) and type III (sensory and motor neuron-derived factor, SMDF) isoforms. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.

Alternate Names

Neuregulin1 beta 1

Gene Symbol

NRG1

Additional Neuregulin-1 beta 1/NRG1 beta 1 Products

Product Documents for Neuregulin-1 beta 1/NRG1 beta 1 Antibody [PE]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Neuregulin-1 beta 1/NRG1 beta 1 Antibody [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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