MyBPC3 Antibody [FITC]
Novus Biologicals, part of Bio-Techne | Catalog # AF7199F
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human, Mouse
Applications
Western Blot
Label
FITC (Excitation = 495 nm, Emission = 519 nm)
Antibody Source
Polyclonal Sheep IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant mouse MyBPC3
Arg998-Lys1100
Accession # O70468
Arg998-Lys1100
Accession # O70468
Specificity
Detects human and mouse MyBPC3 in Western blots and in direct ELISAs.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for MyBPC3 Antibody [FITC]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: MyBPC3
Cardiac myosin binding protein C3 (MyBPC3) is a 140 kDa thick filament-associated protein located in the crossbridge region of cardiac muscle sarcomeres. It is composed of eight Ig-like domains and three fibronectin 3-like domains and is known to be a physiological substrate of cAMP-dependent protein kinase. MyBPC3 has a role in sarcomeric structure and in the regulation of cardiac muscle contraction. MyBPC3 is released into the coronary effluent during myocardial infarction. Mutations in MyBPC3 are associated with hypertrophic cardiomyopathy.
Long Name
Myosin Binding Protein C, Cardiac
Alternate Names
C-protein, cardiac muscle isoform, CMH4, FHC, MYBP-C
Gene Symbol
MYBPC3
Additional MyBPC3 Products
Product Documents for MyBPC3 Antibody [FITC]
Product Specific Notices for MyBPC3 Antibody [FITC]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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