Mouse OCILRP2/CLEC2i Alexa Fluor™ Plus 488-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # AF3370AFP488

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AF3370AFP488-100UG
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Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Goat IgG

View all OCILRP2/CLEC2i Antibodies »

Product Specifications

Specificity

Detects mouse OCILRP2/CLEC2i in direct ELISAs and Western blots. In Western blots, approximately 25% cross-reactivity with recombinant mouse OCIL is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Background: OCILRP2/CLEC2i

OCILRP2, also known as CLRG (C-type lectin related g) and CLEC2i (C-type lectin domain family 2, member i), is a type II transmembrane protein whose gene has been mapped to the natural killer gene complex (NKC) on mouse chromosome 6. By alternative splicing, multiple isoforms exist. OCIL RP2 is expressed on osteoclasts, chondrocytes and lymphoid cell types. It is a ligand for NKrp1f (KLRB1f), another NK receptor on the NKC. OCILRP2 inhibits osteoclast formation and can affect NK cell functions. The extracellular domain of mouse OCILRP2 shares 79% and 74% amino acid sequence identity with that of mouse OCILRP1 and OCIL, respectively. A human OCILRP2 ortholog has not been identified.

Long Name

Osteoclast Inhibitory Lectin Related Protein 2

Alternate Names

CLEC2i, CLRG

Entrez Gene IDs

93675 (Mouse)

Gene Symbol

CLEC2I

UniProt

Q9WVF9

Additional OCILRP2/CLEC2i Products

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Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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