Mouse CD161/NK1.1 APC‑conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB8319A
Discontinued Product
FAB8319A has been discontinued.
View all CD161/NK1.1 products.
Key Product Details
Species Reactivity
Mouse
Applications
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # PK136
Product Specifications
Immunogen
Mouse NK-1+ splenocytes and bone marrow cells
Specificity
Detects mouse CD161/NK1.1 by flow cytometry
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Mouse CD161/NK1.1 APC‑conjugated Antibody
Detection of CD161/NK1.1 in C57BL/6 Mouse Splenocytes by Flow Cytometry.
C57BL/6 mouse splenocytes were stained with Rat Anti-Mouse NKp46/NCR1 PE-conjugated Monoclonal Antibody (Catalog # FAB22252P) and either (A) Mouse Anti-Mouse CD161/NK1.1 APC-conjugated Monoclonal Antibody (Catalog # FAB8319A) or (B) Mouse IgG2AAllophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.Applications for Mouse CD161/NK1.1 APC‑conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: C57BL/6 mouse splenocytes
Sample: C57BL/6 mouse splenocytes
Spectra Viewer
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
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Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CD161/NK1.1
CD161, also known as NK1.1, KLRB-1C, Ly-55, and NKR-P1c, is a 28 kDa type 2 transmembrane protein in the Killer Cell Lectin-like Receptor family. CD161 is expressed as a disulfide-linked homodimer on the surface of NK cells and subpopulations of NKT, CD4+, CD8+, and gamma/ delta T cells. Its cross-linking on NK cells induces cytolytic activity, and on CD4 cells it promotes IgE production and the expansion of Th2 responses. Mature mouse CD161 consists of a 45 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 157 aa extracellular domain with one C-type lectin domain.
Additional CD161/NK1.1 Products
Product Documents for Mouse CD161/NK1.1 APC‑conjugated Antibody
Product Specific Notices for Mouse CD161/NK1.1 APC‑conjugated Antibody
For research use only
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