Mouse CD161/NK1.1 APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB7614A

Discontinued Product
FAB7614A has been discontinued. View all CD161/NK1.1 products.

Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Rat IgG2A Clone # 694370

View all CD161/NK1.1 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse CD161/NK1.1
Val62-Ser220
Accession # P27814

Specificity

Detects mouse CD161/NK1.1 expressed specifically in the C57/B6 mouse strain. No detection of  CD161/NK1.1 was observed in the BALB/c mouse strain. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse (rm) KLRB-1B is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Scientific Data Images for Mouse CD161/NK1.1 APC-conjugated Antibody

Detection of CD161/NK1.1 antibody in Mouse Splenocytes antibody by Flow Cytometry.

Detection of CD161/NK1.1 in Mouse Splenocytes by Flow Cytometry.

Mouse splenocytes were stained with Rat Anti-Mouse NKp46/NCR1 PE-conjugated Monoclonal Antibody (Catalog # FAB22252P) and either (A) Rat Anti-Mouse CD161/NK1.1 APC-conjugated Monoclonal Antibody (Catalog # FAB7614A) or (B) Rat IgG2AAllophycocyanin Isotype Control (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins.

Applications for Mouse CD161/NK1.1 APC-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Mouse splenocytes

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD161/NK1.1

CD161, also known as NK1.1, KLRB-1C, Ly-55, and NKR-P1c, is a 28 kDa type 2 transmembrane protein in the killer cell lectin-like receptor family. CD161 is expressed as a disulfide-linked homodimer on the surface of NK cells and subpopulations of NKT, CD4+, CD8+, and gamma/ delta T cells. Its cross-linking on NK cells induces cytolytic activity, and on CD4 cells it promotes IgE production and the expansion of Th2 responses. Mature mouse CD161 consists of a 45 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 157 aa extracellular domain with one C-type lectin domain.

Alternate Names

Klrb1c, Ly-59, Ly55c

Entrez Gene IDs

17059 (Mouse)

Gene Symbol

KLRB1C

UniProt

P27814

Additional CD161/NK1.1 Products

Product Documents for Mouse CD161/NK1.1 APC-conjugated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse CD161/NK1.1 APC-conjugated Antibody

For research use only

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