MMP21 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-47081

Novus Biologicals, part of Bio-Techne
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NBP3-47081
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MMP21 Antibodies »

Product Specifications

Immunogen

matrix metallopeptidase 21. (Uniprot# Q8N119)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

67 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit MMP21 Antibody - BSA Free (NBP3-47081) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for MMP21 Antibody - BSA Free

MMP21 Antibody - BSA Free

Immunohistochemistry: MMP21 Antibody - BSA Free [NBP3-47081] -

Immunohistochemistry: MMP21 Antibody - BSA Free [NBP3-47081] - Immunohistochemistry of paraffin-embedded human skin cancer tissue slide using (MMP21 Antibody) at dilution of 1:50
MMP21 Antibody - BSA Free

Western Blot: MMP21 Antibody - BSA Free [NBP3-47081] -

Western Blot: MMP21 Antibody - BSA Free [NBP3-47081] - Mouse liver tissue were subjected to SDS PAGE followed by western blot with (MMP21 Antibody) at dilution of 1:600

Applications for MMP21 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MMP21

Matrix metalloproteinases (MMPs) play key roles in tissue remodelling under normal development and, especially, in diseases ranging from malignancies to stroke. Expression of MMP-21 is controlled uniquely by Pax and Notch transcription factors known to be critical for organogenesis. MMP-21 is expressed transiently in mouse embryogenesis and increased in embryonic neuronal tissues. Observations indicate that there is an important specific function for MMP-21 in embryogenesis, especially in neuronal cells (1). MMP-21 is expressed in various human fetal and adult tissues as well as in cancer cell lines. MMP-21 protein can also be detected in malignancies such as ovarian and colon carcinomas by immunohistochemical staining. Findings suggest that MMP-21 functions in embryogenesis and tumor progression (2). Results suggest that during development, MMP-21 expression is temporally and spatially tightly controlled. Unlike many classical MMPs, it is present in various normal adult tissues. Among epithelial MMPs, MMP-21 has a unique expression pattern in cancer (3).

Long Name

Matrix metalloproteinase-21

Alternate Names

MMP-21

Gene Symbol

MMP21

Additional MMP21 Products

Product Documents for MMP21 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MMP21 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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