Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

HRP

Antibody Source

Monoclonal Mouse IgG1 Clone # 213816

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MIS/AMH Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human MIS/AMH
Ala453-Arg560
Accession # NP_000470

Specificity

Detects human MIS/AMH in direct ELISAs and Western blots. Shows approximately 50-100% cross-reactivity with recombinant mouse (rm) MIS and recombinant rat MIS and no cross-reactivity with recombinant human (rh) ART, rmArtemin, rhCripto-1, recombinant drosophila Dpp, rhGDNF, rhLAP, rhLatent TGF-beta 1, rhLefty-A (short and long isoforms), rmLefty-1 (short and long isoforms), rhNeurturin, rmNodal, rhTGF-alpha, recombinant amphibian TGF-beta 5, rhTGF-beta 1, rhTGF-beta 1.2, rhTGF-beta 2, rhTGF-beta 3, or rmWIF-1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for MIS/AMH Antibody (213816) [HRP]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MIS/AMH

Müllerian inhibiting substance (MIS), also named anti-Müllerian hormone (AMH), is a tissue-specific TGF-beta superfamily growth factor. Its expression is restricted to Sertoli cells of fetal and postnatal testis, and to granulosa cells of postnatal ovary. MIS is synthesized and secreted as a disulfide-linked homodimeric propeptide. Proteolytic cleavage is required to separate the N-terminal proregion from the C-terminal bioactive peptide. Both fragments remain associated in a non-covalent complex. The C-terminal sequence forms a cysteine knot via seven canonical cysteine residues found in TGF-beta superfamily members.

Long Name

Mullerian-inhibiting Substance/Anti-Mullerian Hormone

Alternate Names

AMH

Gene Symbol

AMH

Additional MIS/AMH Products

Product Documents for MIS/AMH Antibody (213816) [HRP]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MIS/AMH Antibody (213816) [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.