Lubricin/PRG4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-19048

Novus Biologicals, part of Bio-Techne
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NBP1-19048
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Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all Lubricin/PRG4 Antibodies »

Product Specifications

Immunogen

Synthetic peptide derived from N terminal domain of PRG4 protein

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 23705804).

Specificity

Reacts specifically with human 151 kDa protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Lubricin/PRG4 Antibody

Immunohistochemistry: Lubricin/PRG4 Antibody [NBP1-19048]

Immunohistochemistry: Lubricin/PRG4 Antibody [NBP1-19048]

Lubricin-PRG4-Antibody-Immunohistochemistry-NBP1-19048-img0002.jpg
Immunohistochemistry: Lubricin/PRG4 Antibody [NBP1-19048]

Immunohistochemistry: Lubricin/PRG4 Antibody [NBP1-19048]

Lubricin-PRG4-Antibody-Immunohistochemistry-NBP1-19048-img0001.jpg

Applications for Lubricin/PRG4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50 - 1:200

Western Blot

1:200-1:1000
Application Notes
IHC-P, IHC reactivity reported in scientific literature (PMID: 23705804), (23083677).

Formulation, Preparation, and Storage

Purification

Unpurified

Reconstitution

Lyophilized powder, reconstituted in distilled water.

Formulation

Antiserum

Preservative

No Preservative

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lubricin/PRG4

Lubricin is a glycoprotein encoded by the PRG4 gene. It has been identified as a component of joint lubrication and synovial homeostasis by reducing friction in joints and preventing synovial cell overgrowth. It is a large, water soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL). Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder.

Long Name

Proteoglycan 4

Alternate Names

CACP, HAPO, Hemangiopoietin, JCAP, MSF, PRG4, Proteoglycan 4, SZP

Entrez Gene IDs

10216 (Human); 96875 (Mouse)

Gene Symbol

PRG4

UniProt

Q92954 (Human)

Additional Lubricin/PRG4 Products

Product Documents for Lubricin/PRG4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Lubricin/PRG4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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