LRIG1 Antibody [DyLight 550]
Novus Biologicals, part of Bio-Techne | Catalog # AF3688L
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
CyTOF-ready, Flow Cytometry, Immunocytochemistry, Western Blot
Label
DyLight 550 (Excitation = 562 nm, Emission = 576 nm)
Antibody Source
Polyclonal Goat IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse LRIG1
Ala37-Thr794
Accession # P70193
Ala37-Thr794
Accession # P70193
Specificity
Detects mouse LRIG1 in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) LRIG1 is observed and less than 5% cross-reactivity with rhLRIG3 is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for LRIG1 Antibody [DyLight 550]
Application
Recommended Usage
CyTOF-ready
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Immunocytochemistry
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: LRIG1
LRIG1 (leucine-rich repeat and Ig-like domain-containing-1) is a 145 kDa type I transmembrane glycoprotein that shares 45 - 50% amino acid (aa) identity with two other mammalian LRIG proteins. LRIG1 shows highest expression in subsets of glial cells in brain, and certain epithelia in liver, stomach, small intestine and skeletal muscle. Within the cell, LRIG1 is expressed in the perinuclear region as well as on the surface. LRIG1 binds ErbB receptors and promotes their ubiquitination, internalization and destruction.
Long Name
Leucine-rich Repeats and Immunoglobulin-like Domains 1
Alternate Names
Img, LIG1
Gene Symbol
LRIG1
Additional LRIG1 Products
Product Documents for LRIG1 Antibody [DyLight 550]
Product Specific Notices for LRIG1 Antibody [DyLight 550]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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