LOX Antibody (23GB920)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-50903

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NBP3-50903-100ul
NBP3-50903-20ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 23GB920

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Lysyl Oxidase/LOX Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human LOX (Uniprot: P28300)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LOX Antibody (23GB920)

LOX Antibody (23GB920)

Flow Cytometry: LOX Antibody (23GB920)[NBP3-50903] -

Flow cytometric analysis of LOXexpression in HT-1080 cells using LOX antibody ((isotype control; red, LOX.
LOX Antibody (23GB920)

Western Blot: LOX Antibody (23GB920)[NBP3-50903] -

Western blotting analysis using LOX antibody (1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:50,000) respectively. Image was developed using FeQ(TM) ECL Substrate Kit.

Applications for LOX Antibody (23GB920)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Lysyl Oxidase/LOX

Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. LOX plays a vital role in the formation and repair of the extracellular matrix. In addition, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, Lysyl oxidase is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.

Long Name

Lysyl Oxidase

Alternate Names

AAT10

Gene Symbol

LOX

Additional Lysyl Oxidase/LOX Products

Product Documents for LOX Antibody (23GB920)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for LOX Antibody (23GB920)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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