T-cell activation requires stimulation of the T-cell receptor (TCR; see MIM 186880)-CD3 (see CD3Z; MIM 186780) complex, followed by recruitment of an array of intracellular signaling proteins (e.g., GRB2 (MIM 108355) and PLCG1 (MIM 172420)). Mediating the interaction between the extracellular receptors and intracellular signaling pathways are adaptor proteins such as LAT (MIM 602354), TRIM (MIM 604962), and LNK.[supplied by OMIM]

Long Name

Lymphocyte Adapter Protein

Alternate Names

SH2B3

Gene Symbol

SH2B3

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Product Documents for LNK/SH2B3 Antibody [Janelia Fluor® 549]

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Product Specific Notices for LNK/SH2B3 Antibody [Janelia Fluor® 549]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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LNK/SH2B3 Antibody [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # AF5888I

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Applications for LNK/SH2B3 Antibody [Janelia Fluor® 549]

Western Blot

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Background: LNK/SH2B3