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Latrophilin 3/LPHN3 Antibody

Catalog # NBP1-82963 | Novus Biologicals a Bio-Techne Brand
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NBP1-82963
NBP1-82963-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Latrophilin 3/LPHN3 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DNLLYVWNNYHVVKYSLDFGPLDSRSGQAHHGQVSYISPPIHLDSELERPSVKDISTTGPLGMGSTTTSTTLRTTTLSPGRSTTPSVSGRRNRSTSTPSPAVEVLDDMTTHLPSASSQIPALEESCEAVEAREIMWFKTRQGQIAKQPCP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Latrophilin 3/LPHN3 Antibody

Immunohistochemistry-Paraffin: Latrophilin 3/LPHN3 Antibody [NBP1-82963] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Applications for Latrophilin 3/LPHN3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Latrophilin 3/LPHN3

Latrophilin-3 is a brain-specific, Ca2+-independent Orphan-B Receptor with an unknown ligand. Unlike the other two latrophilins, Latrophilin-3 does not bind alpha-latrotoxin. Latrophilin-3, like its isoforms, shares homology with lectin, olfactomedin, and transmembrane domains, and possesses variable C-termini and various alternative-splicing sites. Latrophilin-3 has been reported in brain. ESTs have been isolated from B-cell/lung/testis, brain, ear, eye, heart, heart/melanocyte/uterus, kidney, lung, nerve, placenta, and testis libraries.

Alternate Names

CIRL3, LEC3, Lectomedin-3, LPHN3

Gene Symbol

ADGRL3

Product Documents for Latrophilin 3/LPHN3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Latrophilin 3/LPHN3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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