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Key Product Details

Species Reactivity

Human

Applications

Label

mFluor Violet 450 SE (Excitation = 406 nm, Emission = 445 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 327318

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Latent TGF‑ beta bp2/LTBP‑2
Gln36-Glu1821
Accession # NP_000419

Specificity

Detects human Latent TGF‑ beta bp2/LTBP‑2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse LTMP-4 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Latent TGF-beta bp2/LTBP-2

LTBP2, also known as latent-transforming growth factor beta-binding protein 2, is a 195 kDa, 1,821 amino acid protein that is involved in assembly and organization of cellular structure as a member of the latent transforming growth factor=beta binding protein (LTBP) family. Current research is being conducted to study the effect of the protein on diseases and disorders such as fibrosis, primary congenital glaucoma type 3D, carcinoma, hepatitis, melanoma, corneal edema, Weill-Marchesani Syndrome, and pancreatitis. The protein interacts in elastic fiber formation, paxillin interaction, mitochondrial apoptosis, extracellular matrix organization, and molecular mechanisms of cancer pathways with other proteins including FYN, FBLN5, and ABL1.

Alternate Names

Latent TGFbeta bp2, LTBP-2, LTBP2

Gene Symbol

LTBP2

Additional Latent TGF-beta bp2/LTBP-2 Products

Product Documents for Latent TGF-beta bp2/LTBP-2 Antibody (327318) [mFluor Violet 450 SE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Latent TGF-beta bp2/LTBP-2 Antibody (327318) [mFluor Violet 450 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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