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Kv1.1 Antibody (HL3162)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48774

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-48774

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HL3162

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

The immunogen used to generate this antibody corresponds to human Kv1.1.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit Kv1.1 Antibody (HL3162) (NBP3-48774) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for Kv1.1 Antibody (HL3162)

Kv1.1 Antibody (HL3162)

Western Blot: Kv1.1 Antibody (HL3162) [NBP3-48774] -

Boiled and unboiled rat tissue extract (50 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Kv1.1 antibody [HL3162] (NBP3-48774) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
Kv1.1 Antibody (HL3162)

Western Blot: Kv1.1 Antibody (HL3162) [NBP3-48774] -

Untreated (-) and treated (+) boiled and unboiled mouse tissue extract (50 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Kv1.1 antibody [HL3162] (NBP3-48774) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for Kv1.1 Antibody (HL3162)

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Kv1.1

Kv1.1 belongs to a (Shaker) subfamily of the pota ium channel family. It is a major constituent of presynaptic A-type channels that modulate synaptic transmi ion in CNS neurons. Kv1.1-containing channels have been shown to be complexed with Lgi1, which is causative for an autosomal dominant form of lateral temporal lobe epilepsy. In the hippocampus Kv1.1 and Lgi1 are coa embled with Kv1.4 and Kv 1 in axonal terminals. Kv1.1 is an abundant Kv subunit in the brain that is found predominantly localized to axons and nerve terminals. Mutations in human Kv1.1 result in the dominant disorder Episodic Ataxia Type 1.

Long Name

Potassium voltage-gated channel subfamily A member 1

Alternate Names

KCNA1

Gene Symbol

KCNA1

Additional Kv1.1 Products

Product Documents for Kv1.1 Antibody (HL3162)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Kv1.1 Antibody (HL3162)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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