JAM-A Antibody (DMC278) - Chimeric

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48306

Recombinant Monoclonal Antibody
Catalog #
Availability
Size / Price
Qty
NBP3-48306-100ug
NBP3-48306-10ug
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # DMC278

Concentration

LYOPH mg/ml

View all JAM-A Antibodies »

Product Specifications

Immunogen

JAM-A recombinant protein expressed in mammalian cells (Accession# Q9Y624). The exact amino acid sequence is proprietary.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Description

This product is shipped at ambient temperature. Store at -20C to -80C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80C (Avoid repeated freezing and thawing).

Scientific Data Images for JAM-A Antibody (DMC278) - Chimeric

JAM-A Antibody (DMC278) - Chimeric

Flow Cytometry: JAM-A Antibody (DMC278) - Chimeric [NBP3-48306]

JAM-A protein is highly expressed on the surface of HEK293 cell membrane. Flow cytometry analysis with Anti-JAM-A (DMC278) on HEK293 cells transfected with human JAM-A (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram), and Isotype antibody on HEK293 transfected with irrelevant protein (Orange histogram).
JAM-A Antibody (DMC278) - Chimeric

Flow Cytometry: JAM-A Antibody (DMC278) - Chimeric [NBP3-48306]

Flow cytometry analysis of antigen binding of anti-human JAM-A mAb(NBP3-48306). (A) NBP3-48306 does not bind to CHO-S cells that do not express JAM-A. (B) A clear peak shift of NBP3-48306 was seen compared to the control when incubated with JAM-A-expressing AGS cells, indicating strong binding of NBP3-48306 to JAM-A. Antibodies were incubated at 5 ug/mL.

Applications for JAM-A Antibody (DMC278) - Chimeric

Application
Recommended Usage

Flow Cytometry

1:100

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified from cell culture supernatant

Reconstitution

Dissolve the lyophilized antibody in sterile and low endotoxin water. The recommend volume of water is lot specific. Please refer to the instructions printed on the product vial or contact technical support.

Formulation

PBS, pH 7.4, 5-8% Trehalose

Preservative

Trehalose

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Background: JAM-A

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Long Name

Junctional Adhesion Molecule A

Alternate Names

CD321, F11R, JAMA, PAM-1

Gene Symbol

F11R

Additional JAM-A Products

Product Documents for JAM-A Antibody (DMC278) - Chimeric

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for JAM-A Antibody (DMC278) - Chimeric

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.