Irisin/FNDC5 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12317
Key Product Details
Species Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunoprecipitation
Label
Unconjugated
Antibody Source
Polyclonal Rabbit
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Synthetic peptide corresponding to unique amino acid sequences on human FNDC5 protein.
Clonality
Polyclonal
Host
Rabbit
Scientific Data Images for Irisin/FNDC5 Antibody
![Western Blot: Irisin/FNDC5 Antibody [NBP3-12317]](https://resources.bio-techne.com/images/products/Irisin-FNDC5-Antibody-Western-Blot-NBP3-12317-img0002.jpg "Western Blot: Irisin/FNDC5 Antibody [NBP3-12317]")
Western Blot: Irisin/FNDC5 Antibody [NBP3-12317]
Western Blot: Irisin/FNDC5 Antibody [NBP3-12317] - 1:500 antibody dilution in DiluObuffer. Apparent MW is 45 KDa.![Immunohistochemistry-Paraffin: Irisin/FNDC5 Antibody [NBP3-12317]](https://resources.bio-techne.com/images/products/Irisin-FNDC5-Antibody-Immunohistochemistry-Paraffin-NBP3-12317-img0001.jpg "Immunohistochemistry-Paraffin: Irisin/FNDC5 Antibody [NBP3-12317]")
Immunohistochemistry-Paraffin: Irisin/FNDC5 Antibody [NBP3-12317]
Immunohistochemistry-Paraffin: Irisin/FNDC5 Antibody [NBP3-12317] - Mouse Heart. 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin Qs (blue) counterstain. 40X magnification.Applications for Irisin/FNDC5 Antibody
Application
Recommended Usage
ELISA
1:10000
Immunohistochemistry
1:50-1:150
Immunohistochemistry-Paraffin
1:50-1:150
Immunoprecipitation
1:200
Western Blot
1:500
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
Preservative
0.02% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
Background: Irisin/FNDC5
Irisin, also known as FNDC5, is a peptide hormone that is upregulated in skeletal muscle and subcutaneous adipose tissue during exercise. It induces expression of the mitochondrial proteins PPAR-gamma coactivator 1 alpha (PGC1a) and uncoupling protein-1 (UCP1). It contributes to the regulation of diabetes and obesity by inducing the transition of white adipose tissue into more metabolically active beige adipose tissue. Irisin also regulates neuronal cell differentiation, neurite outgrowth, and osteoblast differentiation.
Long Name
Fibronectin Type III Domain Containing 5
Alternate Names
FNDC5, FRCP2
Gene Symbol
FNDC5
Additional Irisin/FNDC5 Products
Product Specific Notices for Irisin/FNDC5 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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