Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 1056111

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Irisin/FNDC5 Antibodies »

Product Specifications

Immunogen

Synthetic peptide covering the C-term of the Irisin peptide sequences of the FNDC5 gene.

Glu97-Glu143
Accession # Q8NAU1

Specificity

Detects Irisin peptide in direct ELISA.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Irisin/FNDC5 Antibody (1056111) [FITC]

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Irisin/FNDC5

Irisin, also known as FNDC5, is a peptide hormone that is upregulated in skeletal muscle and subcutaneous adipose tissue during exercise. It induces expression of the mitochondrial proteins PPAR-gamma coactivator 1 alpha (PGC1a) and uncoupling protein-1 (UCP1). It contributes to the regulation of diabetes and obesity by inducing the transition of white adipose tissue into more metabolically active beige adipose tissue. Irisin also regulates neuronal cell differentiation, neurite outgrowth, and osteoblast differentiation.

Long Name

Fibronectin Type III Domain Containing 5

Alternate Names

FNDC5, FRCP2

Additional Irisin/FNDC5 Products

Product Documents for Irisin/FNDC5 Antibody (1056111) [FITC]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Irisin/FNDC5 Antibody (1056111) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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