Integrin beta 7 Antibody (FIB504) [Alexa Fluor™ Plus 647] - Chimeric
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81086AFP647
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human, Mouse
Applications
Block/Neutralize, Flow Cytometry, Immunocytochemistry/ Immunofluorescence
Label
Alexa Fluor Plus 647
Antibody Source
Recombinant Monoclonal Rabbit IgG Kappa Clone # FIB504
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
FIB504 was prepared by immunizing rats with TK1 cells.
Specificity
FIB504 recognizes an epitope on Integrin beta 7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG Kappa
Applications for Integrin beta 7 Antibody (FIB504) [Alexa Fluor™ Plus 647] - Chimeric
Application
Recommended Usage
Block/Neutralize
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Immunocytochemistry/ Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Integrin beta 7
Alternate Names
ITGB7
Gene Symbol
ITGB7
Additional Integrin beta 7 Products
Product Specific Notices for Integrin beta 7 Antibody (FIB504) [Alexa Fluor™ Plus 647] - Chimeric
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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