Integrin alpha V beta 6 Antibody (7k) [Alexa Fluor™ Plus 488]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-50448AFP488
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Concentration
Product Specifications
Immunogen
Specificity
Clonality
Host
Isotype
Applications for Integrin alpha V beta 6 Antibody (7k) [Alexa Fluor™ Plus 488]
CyTOF-ready
ELISA
Flow Cytometry
Immunocytochemistry/ Immunofluorescence
Immunohistochemistry
Immunoprecipitation
Western Blot
Formulation, Preparation, and Storage
Purification
Formulation
Preservative
Concentration
Shipping
Stability & Storage
Background: Integrin alpha V beta 6
Integrin alpha V beta 6 (aVb6) is a heterodimeric adhesion protein that is exclusively expressed on subsets of epithelial cells, especially during development, after injury or inflammation, or on many carcinomas. Active aVb6 binds to the extracellular matrix proteins Fibronectin and Tenascin C as well as the TGF-beta latency-associated peptide (LAP). It cooperates with LTBP-1, Fibronectin, and PAR-1 to activate TGF-beta 1 or TGF-beta 3 from large latent complexes. aVb6 also plays a role in Treg development, tumor progression, and virus cellular entry.
Alternate Names
Gene Symbol
Additional Integrin alpha V beta 6 Products
Product Documents for Integrin alpha V beta 6 Antibody (7k) [Alexa Fluor™ Plus 488]
Product Specific Notices for Integrin alpha V beta 6 Antibody (7k) [Alexa Fluor™ Plus 488]
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.