Integrin alpha 2/CD49b Antibody (CL7318) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76483

Novus Biologicals, part of Bio-Techne
Catalog #
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NBP2-76483
NBP2-76483-25ul
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Conjugate
Catalog #
Alexa Fluor 350
NBP3-44393AF350
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Alexa Fluor 405
NBP3-44393AF405
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Alexa Fluor 488
NBP3-44393AF488
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Alexa Fluor 532
NBP3-44393AF532
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Alexa Fluor 594
NBP3-44393AF594
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Alexa Fluor 647
NBP3-44393AF647
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Alexa Fluor 700
NBP3-44393AF700
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Alexa Fluor 750
NBP3-44393AF750
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Alexa Fluor Plus 488
NBP3-44393AFP488
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Alexa Fluor Plus 555
NBP3-44393AFP555
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Alexa Fluor Plus 594
NBP3-44393AFP594
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Alexa Fluor Plus 647
NBP3-44393AFP647
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Alexa Fluor Plus 680
NBP3-44393AFP680
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Allophycocyanin
NBP3-44393APC
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Biotin
NBP3-44393B
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CoraFluor 1
NBP3-44393CL1
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DyLight 350
NBP3-44393UV
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DyLight 405
NBP3-44393V
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DyLight 488
NBP3-44393G
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DyLight 550
NBP3-44393R
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DyLight 594
NBP3-44393DL594
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DyLight 650
NBP3-44393C
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DyLight 680
NBP3-44393FR
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DyLight 755
NBP3-44393IR
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FITC
NBP3-44393F
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HRP
NBP3-44393H
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Janelia Fluor 525
NBP3-44393JF525
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Janelia Fluor 549
NBP3-44393JF549
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Janelia Fluor 646
NBP3-44393JF646
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Janelia Fluor 669
NBP3-44393JF669
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mFluor Violet 450 SE
NBP3-44393MFV450
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mFluor Violet 500 SE
NBP3-44393MFV500
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mFluor Violet 610 SE
NBP3-44393MFV610
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PE
NBP3-44393PE
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PerCP
NBP3-44393PCP
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL7318

Format

BSA Free

Concentration

1 mg/ml

View all Integrin alpha 2/CD49b Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from P17301, with the exact immunogen sequence remaining proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (80%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Integrin alpha 2/CD49b Antibody (CL7318) - BSA Free

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody (CL7318) [NBP2-76483]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody (CL7318) [NBP2-76483]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody (CL7318) [NBP2-76483] - Analysis in human skin and skeletal muscle tissues. Corresponding ITGA2 RNA-seq data are presented for the same tissues.
Western Blot: Integrin alpha 2/CD49b Antibody (CL7318) [NBP2-76483]

Western Blot: Integrin alpha 2/CD49b Antibody (CL7318) [NBP2-76483]

Western Blot: Integrin alpha 2/CD49b Antibody (CL7318) [NBP2-76483] - Analysis in human cell line RT-4.
Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody (CL7318) [NBP2-76483]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody (CL7318) [NBP2-76483]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody (CL7318) [NBP2-76483] - Staining of human prostate shows moderate membranous postivity in glandular cells.
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Applications for Integrin alpha 2/CD49b Antibody (CL7318) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 2/CD49b

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.

Alternate Names

CD49b, ITGA2, VLA-2 alpha

Gene Symbol

ITGA2

Additional Integrin alpha 2/CD49b Products

Product Documents for Integrin alpha 2/CD49b Antibody (CL7318) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha 2/CD49b Antibody (CL7318) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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