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Key Product Details

Species Reactivity

Mouse

Applications

Immunocytochemistry, Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Sheep IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin alpha11
Phe19-Pro1141
Accession # P61622

Specificity

Detects mouse Integrin alpha11 in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant human (rh) Integrin alpha11 is observed, and less than 2% cross-reactivity with recombinant mouse (rm) Integrin  alpha2 and rmIntegrin alpha10 is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Integrin alpha 11 Antibody [DyLight 488]

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin alpha 11

Integrin alpha-11 is a protein that functions as a heterodimer of an alpha and beta subunit, may be involved in attaching muscle tissue to the extracellular matrix, is most highly expressed in the uterus and heart, and is encoded by a gene comprised of 1188 amino acids with a weight of approximately 133 kDa. Studies are being conducted on several diseases and disorders related to this protein including ADHD, lung cancer, adenocarcinoma, thyroiditis, and prostatitis. Integrin alpha-11 has also been shown to have interactions with ITGB1, COL1A1, COL1A2, ACTB, and ACTG1 in pathways such as the focal adhesion, CDK5, NR-kappaB, integrin-mediated cell adhesion, signal transduction, and ECM-receptor interaction pathways.

Alternate Names

ITGA11

Gene Symbol

ITGA11

Additional Integrin alpha 11 Products

Product Documents for Integrin alpha 11 Antibody [DyLight 488]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Integrin alpha 11 Antibody [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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