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Integrin alpha 1/CD49a Antibody (CL7207) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44430

Novus Biologicals, part of Bio-Techne
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NBP3-44430

Key Product Details

Validated by

Knockout/Knockdown, Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL7207

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

This antibody was generated using a synthetic peptide of P56199, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Novus Biologicals Mouse Integrin alpha 1/CD49a Antibody (CL7207) - Azide and BSA Free (NBP2-76478) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for Integrin alpha 1/CD49a Antibody (CL7207) - Azide and BSA Free

Integrin alpha 1/CD49a Antibody (CL7207) - Azide and BSA Free Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody [NBP3-44430]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody [NBP3-44430]

Analysis in human prostate and skeletal muscle tissues using NBP3-44430 antibody. Corresponding Integrin alpha 1/CD49a RNA-seq data are presented for the same tissues.
Integrin alpha 1/CD49a Antibody (CL7207) - Azide and BSA Free Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody [NBP3-44430]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody [NBP3-44430]

Staining of human prostate shows strong membranous positivity in smooth muscle cells.
Integrin alpha 1/CD49a Antibody (CL7207) - Azide and BSA Free Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody [NBP3-44430]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody [NBP3-44430]

Staining of human skeletal muscle shows no positivity in striated muscle fibers as expected.

Applications for Integrin alpha 1/CD49a Antibody (CL7207) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Use in Block/Neutralize reported in scientific literature (PMID:31750298).

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 1/CD49a

Integrin alpha 1 encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq]

Alternate Names

CD49a, ITGA1, VLA-1

Gene Symbol

ITGA1

Additional Integrin alpha 1/CD49a Products

Product Documents for Integrin alpha 1/CD49a Antibody (CL7207) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Integrin alpha 1/CD49a Antibody (CL7207) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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