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ING2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1044

Novus Biologicals, part of Bio-Techne
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NB100-1044-100ug

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence C-DKSTEKTKKDRRSR corresponding to C-Terminus according to NP_001555.1.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Bovine.

Clonality

Polyclonal

Host

Goat

Scientific Data Images for ING2 Antibody

Western Blot: ING2 Antibody [NB100-1044]

Western Blot: ING2 Antibody [NB100-1044]

Western Blot: ING2 Antibody [NB100-1044] - Staining of HepG2 lysate (RIPA buffer, 35 ug total protein per lane). Antibody at 2 ug/mL. Primary incubated for 12 hour. Detected by chemiluminescence.

Applications for ING2 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:1000

Western Blot

1 - 3 ug/mL
Application Notes
WB: Approx. 30 kDa band observed in hepatocarcinoma HEPG2 lysates (calculated MW of 32.8 kDa band according to NP_001555).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris (pH 7.3), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ING2

This protein is similar to ING1, a tumor suppressor protein that can bind TP53, inhibit cell growth, and induce apoptosis. This protein binds phosphoinositides (PtdInPs) at its plant homeodomain (PHD) domain and it acts as a PtdInPs receptor. PtdInPs binding regulates the ability of this protein to activate TP53 and TP53-dependent apoptosis.

Alternate Names

ING1L, p33ING2

Entrez Gene IDs

3622 (Human)

Gene Symbol

ING2

Additional ING2 Products

Product Documents for ING2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ING2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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