IL-4I1 Antibody (CL9071) - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-88929
Key Product Details
Validated by
Species Reactivity
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Description
Scientific Data Images for IL-4I1 Antibody (CL9071) - BSA Free
Western Blot: IL-4I1 Antibody (CL9071) [NBP2-88929]
Western Blot: IL-4I1 Antibody (CL9071) [NBP2-88929] - Analysis in human cell line HDLM-2.Immunohistochemistry-Paraffin: IL-4I1 Antibody (CL9071) [NBP2-88929]
Immunohistochemistry-Paraffin: IL-4I1 Antibody (CL9071) [NBP2-88929] - Staining of human kidney shows no positivity in cells in glomeruli.Applications for IL-4I1 Antibody (CL9071) - BSA Free
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Background: IL-4I1
Interleukin 4 induced protein 1 (IL-4I1), also known as protein FIG-1 and L-amino acid oxidase, is encoded by a B-cell IL-4-inducible gene, FIG1, and is highly expressed in primary metastinal B-cell lymphomas. It belongs to the flavin monoamine oxidase family, FIG1 subfamily. Enzymological characterization reveals that IL-4I1 has L-amino acid oxidase activity with preference toward aromatic amino acids. Studies have shown that hIL-4I1 inhibited the proliferation of CD3-stimulated T lymphocytes with a similar effect on CD4(+) and CD8(+) T cells. Its inhibitory effect was dependent on enzymatic activity and H2O2 production. Its restricted expression to lymphoid tissues indicates that it may play an important function in the immune system.
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Additional IL-4I1 Products
Product Documents for IL-4I1 Antibody (CL9071) - BSA Free
Product Specific Notices for IL-4I1 Antibody (CL9071) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.