IL-20 R beta/FNDC6 Antibody [CoraFluor™ 1]
Novus Biologicals, part of Bio-Techne | Catalog # AF1788CL1
![IL-20 R beta/FNDC6 Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/af1788cl1_goat-il-20-r-beta-fndc6-pab-corafluor-1-3112202515295913.png "Product Feature: CoraFluor Probes for TR-FRET")
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
CoraFluor 1
Antibody Source
Polyclonal Goat IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human IL-20 R beta
Asp30-Ala230
Accession # Q6UXL0
Asp30-Ala230
Accession # Q6UXL0
Specificity
Detects human IL-20 R beta in direct ELISAs and Western blots. In direct ELISAs, approximately 60% cross-reactivity with recombinant mouse IL-20 R beta is observed and less than 2% cross-reactivity with recombinant human (rh) IL-20 R alpha, rhIL-10 R beta, rhIFN-gamma R1, and rhIFN-gamma R2 is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
CoraFluor(TM) 1, amine reactive
CoraFluor(TM) 1, thiol reactive
For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
CoraFluor(TM) 1, amine reactive
CoraFluor(TM) 1, thiol reactive
For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
Scientific Data Images for IL-20 R beta/FNDC6 Antibody [CoraFluor™ 1]
Product Feature: CoraFluor Probes for TR-FRET
CoraFluor™ 1, amine reactive (Catalog:7920) and CoraFluor™ 2, amine reactive (Catalog # 7950) are terbium-based probes that have been developed for use as TR-FRET donors. They emit wavelengths compatible with commonly used fluorescent acceptor dyes such as BODIPY® (or BDY) and Janelia Fluor® dyes, FITC (Catalog # 5440), TMR and Cyanine 5 (Catalog # 5436). CoraFluor™ fluorescence is brighter and more stable in biological media than existing TR-FRET donors, leading to enhanced sensitivity and improved data generation. CoraFluor™ 1 exhibits excitation upon exposure to a 337 nm UV laser.Applications for IL-20 R beta/FNDC6 Antibody [CoraFluor™ 1]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
PBS
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark. Do not freeze.
Background: IL-20 R beta
IL-20 R alpha (or IL-20 R1) and IL-20 R beta (or IL-20 R2) belong to the class II cytokine receptor family. They form multiple heterodimeric signaling complexes that mediate IL-10 family class II cytokine signals. IL-20 R alpha heterodimerizes with IL-20 R beta to form the functional receptor for IL-19, IL-20 and IL-24. IL-20 R alpha also heterodimerizes with IL-10 R beta to form a functional receptor complex for IL-26, while IL-20 R beta heterodimerizes with IL-22 R to form functional IL-20 and IL-24 receptors. The IL-20 receptors are thought to mediate a number of physiological functions including apoptosis, hematopoiesis, and anti-tumor activities.
Long Name
Interleukin 20 Receptor beta
Alternate Names
DIRS1, FNDC6, IL-20R2, IL-20Rb, IL20R beta, IL20RB
Gene Symbol
IL20RB
Additional IL-20 R beta Products
Product Documents for IL-20 R beta/FNDC6 Antibody [CoraFluor™ 1]
Product Specific Notices for IL-20 R beta/FNDC6 Antibody [CoraFluor™ 1]
CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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