Ikaros/IKZF1 Antibody [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # AF4984B

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

AF4984

Allophycocyanin

AF4984A

CoraFluor 1

AF4984CL1

DyLight 350

AF4984D

DyLight 405

AF4984E

DyLight 488

AF4984K

DyLight 550

AF4984L

DyLight 594

AF4984M

DyLight 650

AF4984W

DyLight 680

AF4984Y

DyLight 755

AF4984Z

FITC

AF4984F

HRP

AF4984H

Janelia Fluor 525

AF4984JF525

Janelia Fluor 549

AF4984I

Janelia Fluor 646

AF4984J

Janelia Fluor 669

AF4984JF669

mFluor Violet 450 SE

AF4984MFV450

mFluor Violet 500 SE

AF4984MFV500

mFluor Violet 610 SE

AF4984MFV610

PE

AF4984P

PerCP

AF4984C

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Intracellular Staining by Flow Cytometry, Immunocytochemistry, Chromatin Immunoprecipitation (ChIP), CyTOF-ready

Label

Biotin

Antibody Source

Polyclonal Goat IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Ikaros Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human lkaros
Ser427-Ser519
Accession # Q13422

Specificity

Detects human lkaros in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross‑reactivity with recombinat human (rh) ZIC-1, rhZNF-24, and rhZNF-206 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Ikaros/IKZF1 Antibody [Biotin]

Application

Recommended Usage

Chromatin Immunoprecipitation (ChIP)

Optimal dilutions of this antibody should be experimentally determined.

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Intracellular Staining by Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Ikaros

Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs)

Long Name

DNA-binding protein Ikaros

Alternate Names

IK1, IKZF1, LyF-1, LYF1, PRO0758, ZNFN1A1

Gene Symbol

IKZF1

Additional Ikaros Products

Product Documents for Ikaros/IKZF1 Antibody [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Ikaros/IKZF1 Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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