IFITM3/Fragilis Antibody [Janelia Fluor® 646]
Novus Biologicals, part of Bio-Techne | Catalog # AF3377J
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Immunohistochemistry, Western Blot
Label
Janelia Fluor 646
Antibody Source
Polyclonal Goat IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant mouse IFITM3/Fragilis
Asn2-His57
Accession # Q9CQW9
Asn2-His57
Accession # Q9CQW9
Specificity
Detects mouse IFITM3/Fragilis in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human IFITM3 is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for IFITM3/Fragilis Antibody [Janelia Fluor® 646]
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: IFITM3/Fragilis
Mouse IFITM3/CD225 (also Fragilis) is a 137 amino acids (aa) 2-transmembrane protein that belongs to the Fragilis family of interferon-inducible genes. It contains two terminal extracellular domains (aas 1 - 57 and 131 - 137) and one cytoplasmic region that potentially allows for multiple phosphorylations. The N-terminal extracellular region of mouse IFITM3 is 54%, 91% and 58% aa identical to the equivalent region in bovine, rat and human IFITM3, respectively. IFITM3 is believed to be involved in primordial germ cell clustering and regionalization.
Long Name
Interferon-induced Transmembrane Protein 3
Alternate Names
Fragilis, IP15, mil-1
Gene Symbol
IFITM3
Additional IFITM3/Fragilis Products
Product Documents for IFITM3/Fragilis Antibody [Janelia Fluor® 646]
Product Specific Notices for IFITM3/Fragilis Antibody [Janelia Fluor® 646]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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