Human Reg3A Alexa Fluor™ Plus 488-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # AF5940AFP488

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AF5940AFP488-100UG
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Sheep IgG

View all Reg3A Antibodies »

Product Specifications

Specificity

Detects human Reg3A in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) Reg3G, recombinant mouse (rm) Reg3A, rmReg3B and recombinant rat Reg2 is observed and less than 2% cross-reactivity with rhReg1A, rhReg1B, rmRegIV, rmReg2 and rmReg3D.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Human Reg3A Alexa Fluor™ Plus 488-conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Background: Reg3A

Reg3A (regenerating gene III alpha) is a secreted, 17 kDa, type III member of the Reg family, C-type lectin superfamily of proteins. It is expressed in intestine and exocrine pancreas, where it may have a protective effect against infection and TNF-alpha -induced stress. Mature mouse Reg3A is 149 amino acids (aa) in length (aa 27‑175). It is essentially a soluble C-type lectin domain (aa 40‑173). There are four type III genes ( alpha-delta) in the mouse Reg family. Reg3A has less that 60% aa identity to beta-delta. Mature mouse Reg3A is 87% and 61% aa identical to rat and human Reg3A, respectively.

Long Name

Regenerating Islet-derived IIIa

Alternate Names

Lithostathine 3, PAP2, REG3A

Entrez Gene IDs

5068 (Human); 19694 (Mouse); 171162 (Rat)

Gene Symbol

REG3A

UniProt

Q06141 (Human)

Additional Reg3A Products

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Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Reg3A Alexa Fluor™ Plus 488-conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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