Human/Mouse Wnt-5a Antibody
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Species Reactivity: | Human, Mouse |
Immunogen: |
CHO-derived recombinant mouse Wnt-5a Gln38-Lys380 Accession # P22725 |
Applications: | Immunohistochemistry, Western Blot |
Label: | Unconjugated |
Source: | Monoclonal Rat IgG2A Clone # 442625 |
Specificity: |
Detects mouse Wnt-5a in direct ELISAs and human and mouse Wnt‑5a in Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse Wnt-1, 2b, 3a, 4, 5b, 8a, 8b, 9b, 10a, 10b, 11, or 16 is observed. |
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Citations for Human/Mouse Wnt-5a Antibody (17)
Citations are publications that use Bio-Techne products. Selected citations for Human/Mouse Wnt-5a Antibody include:
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Species: Mouse
Sample Types: Whole Tissue
Applications: IHCGJ Lee et al. (2022), YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity Cell Death Disease, 2022;13(4):407.
PMID: 35478181 -
Species: Human
Sample Types: Protein Extracts
Applications: Western BlotV Yadav et al. (2022), Increased MARCKS Activity in BRAF Inhibitor-Resistant Melanoma Cells Is Essential for Their Enhanced Metastatic Behavior Independent of Elevated WNT5A and IL-6 Signaling Cancers, 14(24).
PMID: 36551563 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotY Shao et al. (2021), HDAC6 suppresses microRNA-199a transcription and augments HPV-positive cervical cancer progression through Wnt5a upregulation The international journal of biochemistry cell biology, 2021;0(0):106000.
PMID: 33933678 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: Western BlotT Radaszkiew et al. (2021), RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy Elife, 10(0).
PMID: 34702444 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Asem et al. (2020), Host Wnt5a Potentiates Microenvironmental Regulation of Ovarian Cancer Metastasis Cancer Res., 0(0).
PMID: 31932454 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PTC Huang et al. (2017), Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells PLoS ONE, 12(8):e0181034.
PMID: 28859077 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-FrM Vesel et al. (2017), ABCB1 and ABCG2 drug transporters are differentially expressed in non-small cell lung cancers (NSCLC) and expression is modified by cisplatin treatment via altered Wnt signaling Respir. Res, 18(1):52.
PMID: 28340578 -
Species: Human
Sample Types: Tissue Homogenates
Applications: Western BlotHoeke A Baarsma (2016), Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD J. Exp. Med, 0(0).
PMID: 27979969 -
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot(2016), WNT5A signaling impairs breast cancer cell migration and invasion via mechanisms independent of the epithelial-mesenchymal transition J Exp Clin Cancer Res, 35(1):144.
PMID: 27623766 -
Species: Mouse
Sample Types: Cell Lysates
Applications: Western BlotFuster J et al. (2015), Noncanonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction independent of adipose tissue expansion. Diabetes, 64(4):1235-48.
PMID: 25352637 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotMacMillan et al. (2014), Stage of breast cancer progression influences cellular response to activation of the WNT/planar cell polarity pathway. Sci Rep, 4(0):6315.
PMID: 25204426 -
Species: Human
Sample Types: Protein
Applications: Western BlotYap L et al. (2014), Oncogenic effects of WNT5A in Epstein-Barr virusassociated nasopharyngeal carcinoma. Int J Oncol, 44(5):1774-80.
PMID: 24626628 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotLinnskog R et al. (2014), Interleukin-6 drives melanoma cell motility through p38alpha-MAPK-dependent up-regulation of WNT5A expression. Mol Oncol, 8(8):1365-78.
PMID: 24954857 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCZhao Y et al. (2014), Wnt5a promotes inflammatory responses via nuclear factor kappaB (NF-kappaB) and mitogen-activated protein kinase (MAPK) pathways in human dental pulp cells. J Biol Chem, 289(30):21028-39.
PMID: 24891513 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotPopp T et al. (2014), Wnt5a/beta-catenin signaling drives calcium-induced differentiation of human primary keratinocytes. J Invest Dermatol, 134(8):2183-91.
PMID: 24658506 -
Species: Human
Sample Types: Ascites Fluid
Applications: Western BlotBarbolina MV et al. (2011), Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment. Biochem. J., 437(1):1-12.
PMID: 21668411 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationHasan M et al. (0), Wnt5a causes ROR1 to complex and activate cortactin to enhance migration of chronic lymphocytic leukemia cells. Leukemi33(3):653-661.
PMID: 30568170
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Customer Reviews for Human/Mouse Wnt-5a Antibody (1)
Customer Images
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Application: ICC/IFSample Tested: E11.5 mouse embryo fixed in 4% PFASpecies: MouseVerified Customer | Posted 12/09/2020Staining was done on E11.5 mouse embryo heart sections (Right Ventricle) (4% PFA fixed).Concentration used - 8ug/mL.
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