Human/Mouse/Rat PTP-MEG2 Alexa Fluor® 750-conjugated Antibody

Name: Human/Mouse/Rat PTP-MEG2 Alexa Fluor® 750-conjugated Antibody
Brand: R&D Systems
SKU: FAB2668S

R&D Systems, part of Bio-Techne | Catalog # FAB2668S

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Product Datasheet / COA

Key Product Details

Species Reactivity:	Human, Mouse, Rat
Immunogen:	E. coli-derived recombinant human PTP-MEG2 Glu2-Gln593 Accession # P43378
Applications:	Western Blot
Label:	Alexa Fluor 750 (Excitation=749 nm, Emission=775 nm)
Specificity:	Detects human, mouse, and rat PTP-MEG2.

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Technical Data
Citations / Reviews

Applications

	Recommended Concentration	Sample
Western Blot	Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application.

Formulation, Preparation and Storage

Purification	Protein A or G purified
Formulation	Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

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Background: PTP-MEG2

Megakaryocyte protein tyrosine phosphatase 2 (PTP-MEG2), also known as PTPN9, contains an N-terminal domain homologous to the yeast retinaldehyde binding domain Sec14p and a C-terminal phosphatase domain. The Sec14p domain targets PTP-MEG2 to the membrane of secretory vesicles, where it promotes vesicle fusion. Elevated levels of membrane-bound PTP-MEG2 activity in erythroid progenitor cells are observed in polycythemia vera and may affect responsiveness to colony stimulating factors.

Item	Value
Long Name	Megakaryocyte Protein Tyrosine Phosphatase 2
Entrez Gene IDs	5780 (Human); 56294 (Mouse); 266611 (Rat)
Alternate Names	EC 3.1.3.48, MEG2, PTP-MEG2, PTPMEG2, PTPN9, PTPase MEG2, PTPase-MEG2, Protein-tyrosine phosphatase MEG2, protein tyrosine phosphatase, non-receptor type 9, tyrosine-protein phosphatase non-receptor type 9

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