Human/Mouse NETO2 Alexa Fluor™ Plus 488-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # AF3859AFP488

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AF3859AFP488-100UG
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot, Immunoprecipitation

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Goat IgG

View all NETO2 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human NETO2 isoform 1

Specificity

Detects human and mouse NETO2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant human NETO1 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications

Application
Recommended Usage

Immunoprecipitation

Optimal dilution of this antibody should be experimentally determined.

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: NETO2

NETO2 is a neurospecific type I transmembrane protein belonging to the NETO family of proteins that share homology with the axon guidance receptors, neuropilin and the developmentally important metalloproteinase Tolloid/BMP-1. NETO proteins have two CUB domains, an LDL-receptor class A domain in their extracellular region and a conserved FXNPXY-like domain in the cytoplasmic region. A splice variant of NETO2 that lacks the CUB domains and most of the LDL class A domain has been reported. It is likely that like NETO1, NETO2 may be a synaptic protein with neurological function. Human and mouse NETO2 share 98% amino acid sequence homology in their extracellular domains.

Long Name

Neuropilin [NRP] And Tolloid [TLL]-like 2

Alternate Names

BTCL2, NEOT2

Entrez Gene IDs

81831 (Human); 74513 (Mouse); 307757 (Rat)

Gene Symbol

NETO2

UniProt

Q8NC67

Additional NETO2 Products

Product Documents

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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