Human/Mouse/Bovine Integrin alpha6/CD49f APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB13501A
Clone GoH3 was used by HLDA to establish CD designation
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Mouse, Bovine
Cited:
Human, Mouse, Bovine
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry, Affinity Purification
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Rat IgG2A Clone # GoH3
Product Specifications
Immunogen
Mouse mammary tumor cells
Specificity
Detects human, mouse, and bovine Integrin alpha6/CD49f. Recognizes an epitope in the extracellular domain of the Integrin alpha6 subunit.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Scientific Data Images
Detection of Integrin alpha6/CD49f in Human Blood Lymphocytes by Flow Cytometry.
Human peripheral blood lymphocytes were stained with Rat Anti-Human/Mouse/Bovine Integrin a6/CD49f APC-conjugated Monoclonal Antibody (Catalog # FAB13501A, filled histogram) or isotype control antibody (Catalog # IC006A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Detection of Integrin alpha6/CD49f in Mouse Splenocytes by Flow Cytometry.
Mouse splenocytes were stained with Rat Anti-Human/Mouse/Bovine Integrin a6/CD49f APC-conjugated Monoclonal Antibody (Catalog # FAB13501A) and Rat Anti-Mouse CD3 PE-conjugated Monoclonal Antibody (Catalog # FAB4841P). Quadrant markers were set based on control antibody staining (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins.Applications
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Human peripheral blood lymphocytes and mouse splenocytes
Sample: Human peripheral blood lymphocytes and mouse splenocytes
Spectra Viewer
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectra Viewer
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Integrin alpha 6/CD49f
Integrin alpha6 (also VLA-6, CD49F and ITA6) is a 130-150 kDa member of the Integrin alpha chain family of molecules. Mature Integrin alpha6 is a 1107 amino acid (aa) type I transmembrane glycoprotein that contains a 1027 aa extracellular region and a 93 aa cytoplasmic tail. The ECD is cleaved to generate a disulfide-linked dimer that shows a 125 kDa heavy chain (aa 24-938), and a 30-31 kDa membrane-bound light chain (aa 942-1130). Integrin alpha6 forms a nondisulfide-linked heterodimeric complex with both integrin beta 1 and beta 4. Each complex serves as a receptor for laminin.
Alternate Names
CD49f, ITGA6, Platelet gpl, VLA-6
Gene Symbol
ITGA6
Additional Integrin alpha 6/CD49f Products
Product Specific Notices
For research use only
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