Human LRRC4 Alexa Fluor™ Plus 680-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # AF4995AFP680
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Label
Alexa Fluor Plus 680 (Excitation = 687 nm, Emission = 704 nm)
Antibody Source
Polyclonal Sheep IgG
Product Specifications
Specificity
Detects human LRRC4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human LRRC3 is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Human LRRC4 Alexa Fluor™ Plus 680-conjugated Antibody
Application
Recommended Usage
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
Western Blot
Optimal dilution of this antibody should be experimentally determined.
Background: LRRC4
LRRC4 (Leu-rich repeat/LRR-containing protein 4; also brain tumor-associated protein) is a 55 kDa (predicted) member of the Leu-rich protein family. It is expressed on neurons and astrocytes, and antagonizes the signaling pathways for cytokines and growth factors. It is reduced in expression in tumors. Human LRRC4 is a type I transmembrane protein that is 653 amino acids (aa) in length. It contains a 489 aa extracellular region (aa 39-527), and a 105 aa cytoplasmic domain. The extracellular region shows nine LRRs (aa 74-288), a C2 type Ig-like domain (aa 354-440), and a Thr rich segment (aa 455-526). Over aa 39-527, human LRRC4 is 98% aa identical to both mouse and canine LRRC4, respectively.
Long Name
Leucine-rich Repeat Containing 4
Alternate Names
BAG, NAG14
Gene Symbol
LRRC4
UniProt
Additional LRRC4 Products
Product Specific Notices for Human LRRC4 Alexa Fluor™ Plus 680-conjugated Antibody
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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