Key Product Details

Species Reactivity

Human

Applications

Western Blot, Flow Cytometry

Label

Biotin

Antibody Source

Polyclonal Goat IgG

View all Integrin beta 3/CD61 Antibodies »

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Integrin beta3/CD61
Gly27-Asp718
Accession # P05106

Specificity

Detects human Integrin beta3/CD61 in Western blots. In Western blots, less than 5% cross‑reactivity with recombinant human (rh) Integrin beta1, rhIntegrin beta2 and recombinant mouse Integrin beta6 is observed under reducing conditions.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Integrin  beta3/CD61 Biotinylated Antibody

Application
Recommended Usage

Flow Cytometry

2.5 µg/106 cells
Sample: Human peripheral blood mononuclear cells or platelets

Western Blot

0.1 µg/mL
Sample: Recombinant Human Integrin  beta3/CD61

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available:
Size / Price
Qty

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Integrin beta 3/CD61

Integrin beta3, also called CD61, associates with the Integrin alphaIIb or alphaV subunits to form heterodimeric receptors for collagens, fibronectin, vitronectin, fibrinogen, Von willebrand factor or thrombospondin. alphaIIb/ beta3, also known as GPIIb IIIa (Glycoprotein IIb-IIIa), is expressed on platelets. alphaV/ beta3, also known as vitronectin receptor, is expressed on endothelial cells, some B cells, platelets and monocytes.

Alternate Names

CD61, GP3A, GPIIIA, INGRB3, ITGB3

Entrez Gene IDs

3690 (Human); 16416 (Mouse); 29302 (Rat); 102117791 (Cynomolgus Monkey)

Gene Symbol

ITGB3

UniProt

P05106

Additional Integrin beta 3/CD61 Products

Product Documents for Human Integrin  beta3/CD61 Biotinylated Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Integrin  beta3/CD61 Biotinylated Antibody

For research use only

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