Human Integrin alpha4/CD49d Alexa Fluor™ Plus 488-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # BBA37AFP488
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Adhesion Blockade
Label
Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # 2B4
Product Specifications
Immunogen
U937 human histiocytic lymphoma cell line
Specificity
Detects human Integrin alpha4 subunit (Needham, L.A. et al. (1994) Cell Adhesion and Communication
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications
Application
Recommended Usage
Adhesion Blockade
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
Background: Integrin alpha 4/CD49d
Integrin alpha4, also known as CD49d, is a transmembrane protein that forms heterodimers with beta1 or beta7 integrins. These complexes contribute to the trafficking of many hematopoietic cell types. Integrins alpha4 beta1 (also known as VLA-4) and alpha4 beta7 (LPAM-1) are receptors for fibronectin, VCAM and MAdCAM-1.
Alternate Names
CD49d, ITGA4, VLA-4
Gene Symbol
ITGA4
Additional Integrin alpha 4/CD49d Products
Product Specific Notices
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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