Human IFN-beta Antibody

Name: Human IFN-beta Antibody
Brand: R&D Systems
SKU: 31410-1

R&D Systems, Inc. a Bio-Techne Brand

Catalog # 31410-1

Citations (2)

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Key Product Details

Species Reactivity:	Human
Immunogen:	E. coli-derived recombinant human IFN-beta
Applications:	Block/Neutralize
Label:	Unconjugated
Source:	Polyclonal Rabbit Serum
Specificity:	Detects Human IFN‑ beta

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Applications for Human IFN-beta Antibody

Please Note: Optimal dilutions should be determined by each laboratory for each application.

Formulation, Preparation and Storage

Purification	Antigen Affinity-purified
Formulation	Serum.
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	After receipt, this product should be kept at -70 ˚C or below for retention of full activity. Thaw product vial by incubation in cold tap water until just thawed – the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).

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Background: IFN-beta

Interferon-beta (IFN-beta), along with IFN-alpha and IFN-omega, is a member of the type I interferon family. All three type I interferons share a common cell surface receptor that is composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. Type I interferons were originally described as potent anti-viral molecules produced by virally infected cells.

Item	Value
Long Name	Interferon beta
Entrez Gene IDs	3456 (Human); 15977 (Mouse); 24481 (Rat)
Alternate Names	Fibroblast interferon, IFB, IFBIFNB, IFF, IFN-beta, IFNB, IFNB1, IFNbeta, MGC96956, interferon beta, interferon, beta 1, fibroblast

Citations for Human IFN-beta Antibody (2)

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Citations are publications that use Bio-Techne products. Selected citations for Human IFN-beta Antibody include:

Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Patel MV et al. (2012), Uterine epithelial cells specifically induce interferon-stimulated genes in response to polyinosinic-polycytidylic acid independently of estradiol. PLoS ONE, 7(4):e35654.
PMID: 22558189
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Lee SH et al. (2009), The major outer membrane protein of a periodontopathogen induces IFN-beta and IFN-stimulated genes in monocytes via lipid raft and TANK-binding kinase 1/IFN regulatory factor-3. J. Immunol., 182(9):5823-35.
PMID: 19380831

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Product Documents for Human IFN-beta Antibody

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