Human CD7 Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB7579B
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Biotin
Antibody Source
Monoclonal Mouse IgG2B Clone # 848438
Product Specifications
Immunogen
Human embryonic kidney cell line HEK293-derived human CD7
Ala26-Pro180
Accession # P09564
Ala26-Pro180
Accession # P09564
Specificity
Detects human CD7 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant
mouse CD7 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Scientific Data Images for Human CD7 Biotinylated Antibody
Detection of CD7 in Human PBMC lymphocytes by Flow Cytometry.
Human CD19- PBMC lymphocytes were stained with Mouse Anti-Human CD3e APC-conjugated Monoclonal Antibody (FAB100A) and either (A) Mouse Anti-Human CD7 Biotinylated Monoclonal Antibody (Catalog # FAB7579B) or (B) Mouse IgG2B Isotype Control (IC0041B) followed by Phycoerythrin-conjugated Streptavidin (F0040). Staining was performed using our Staining Membrane Proteins protocol.Applications for Human CD7 Biotinylated Antibody
Application
Recommended Usage
Flow Cytometry
0.25 µg/106 cells
Sample: Human PBMC lymphocytes
Sample: Human PBMC lymphocytes
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitution default not known
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CD7
CD7 (Leu-9) is expressed on T cells, NK cells, myeloid progenitor cells, and CD19+ B progenitor cells. Among CD8+ T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells. CD7 associates in cis with CD3 and CD45 and in trans with SECTM1. Ligation of CD7 co stimulates the activation and proliferation of CD4+ and CD8+ T cells and NK cells. It also enhances integrin-mediated adhesion of these cells to Fibronectin, ICAM-1, and VCAM-1. CD7 additionally mediates the Galectin-1 induced apoptosis of T cells and facilitates the fusion of HIV-1 with target cells.
Alternate Names
CD7, LEU-9, TP41
Gene Symbol
CD7
UniProt
Additional CD7 Products
Product Documents for Human CD7 Biotinylated Antibody
Product Specific Notices for Human CD7 Biotinylated Antibody
For research use only
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