Human CD11b/Integrin alpha M Alexa Fluor® 488-conjugated Antibody

Name: Human CD11b/Integrin alpha M Alexa Fluor® 488-conjugated Antibody
Brand: R&D Systems
SKU: FAB16992G

R&D Systems, part of Bio-Techne | Catalog # FAB16992G

Submit a review

Product Datasheet / COA

Key Product Details

Species Reactivity:	Human
Immunogen:	Mouse myeloma cell line NS0-derived recombinant human CD11b/Integrin Î±M Phe17-Asn1105 Accession # NP_001139280
Applications:	Immunohistochemistry, Western Blot
Label:	Alexa Fluor 488 (Excitation=488 nm, Emission=515-545 nm)
Specificity:	Detects human CD11b/Integrin alpha M in direct ELISAs and Western blots. In Western blots no cross-reactivity with recombinant mouse (rm) Integrins alpha 2, alpha 3, alpha 4, alpha E or rhIntegrins alpha 5, alpha V, beta 1, beta 2, beta 3, or beta 6.

View Full Technical Details for Human CD11b/Integrin alpha M Alexa Fluor® 488-conjugated Antibody

Technical Data
Citations / Reviews

Applications

	Recommended Concentration	Sample
Western Blot	Optimal dilution of this antibody should be experimentally determined.
Immunohistochemistry	Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application.

Formulation, Preparation and Storage

Purification	Protein A or G purified
Formulation	Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: CD11b/Integrin alpha M

The Integrin family proteins are heterodimeric transmembrane receptors composed of an alpha and a beta subunit. The Integrin alpha M subunit, also known as MAC-1 alpha subunit or CD11b, combines with the Integrin beta 2 subunit (CD18) to form the non-covalent heterodimer Integrin alpha M/ beta 2, also known as MAC-1 and complement receptor type 3 (CR3). Integrin alpha M/ beta 2 is expressed on granulocytes, macrophages, dendritic cells and natural killer cells. Upon activation, alpha M/ beta 2 can bind several ligands (including ICAM-1 fibrinogen and the C3 complement fragment C3bi) to mediate phagocyte adhesion, migration and ingestion of complement-opsonized particles.

Entrez Gene IDs

3684 (Human); 16409 (Mouse)

Alternate Names

CD11 antigen-like family member B, CD11b, CD11b antigen, CR-3 alpha chain, CR3A, CR3AMGC117044, Cell surface glycoprotein MAC-1 subunit alpha, Complement component 3 receptor 3 subunit, ITGAM, Integrin alpha M, Leukocyte adhesion receptor MO1, MAC-1, MAC1A, MO1A, Neutrophil adherence receptor, SLEB6, antigen CD11b (p170), integrin alpha-M, integrin, alpha M (complement component 3 receptor 3 subunit), macrophage antigen alpha polypeptide, neutrophil adherence receptor alpha-M subunit

Customer Reviews

There are currently no reviews for this product. Be the first to review Human CD11b/Integrin alpha M Alexa Fluor® 488-conjugated Antibody and earn rewards!

Have you used Human CD11b/Integrin alpha M Alexa Fluor® 488-conjugated Antibody?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review

Product Documents

Product Datasheets

Download Product Datasheets