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Human CCR5 Antibody

Catalog # MAB1801 | R&D Systems, Inc. a Bio-Techne Brand
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MAB1801-100
MAB1801-SP

Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CTC8

Product Summary for Human CCR5 Antibody

Immunogen

CHO Chinese hamster ovary cell line transfected with human CCR5

Specificity

Detects human CCR5 in direct ELISAs and Western blots. For additional information regarding epitope specificity for this antibody and other R&D Systems anti-human CCR5 antibodies, see reference 1 below.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human CCR5 Antibody

Application
Recommended Usage

Immunoprecipitation

Mirzabekov, T. et al. (1999) J. Biol. Chem. 274:28745.

Western Blot

Lee, B. et al. (1999) J. Biol. Chem. 274:9617.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 1 using MAB1801 in the following applications:

Published Applications

Read 6 publications using MAB1801 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CCR5

CCR5 is a G protein-linked seven transmembrane domain chemokine receptor. CCR5 serves as a receptor for several chemokines including MIP-1 alpha, MIP-1 beta, MCP-2, and RANTES. It also functions as a co‑receptor for Macrophage Tropic HIV-1 infection.

References

  1. Lee, B. et al. (1999) J. Biol. Chem. 274:9617.

Alternate Names

CCR5, CD195

Entrez Gene IDs

1234 (Human); 12774 (Mouse); 117029 (Rat); 484789 (Canine); 493769 (Feline)

Gene Symbol

CCR5

Product Documents for Human CCR5 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human CCR5 Antibody

For research use only

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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