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Human CCR5 Alexa Fluor® 750-conjugated Antibody

Human CCR5 Alexa Fluor® 750-conjugated Antibody
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FAB180S-100UG

Key Product Details

Species Reactivity: Human
Immunogen: NS0 mouse myeloma cell line transfected with human CCR5
Met1-Leu352
Accession # P51681
Applications: Flow Cytometry
Label: Alexa Fluor 750 (Excitation=749 nm, Emission=775 nm)
Specificity:

Specifically stains human CCR5 transfectants but not the parental cell line as detected by flow cytometry. It has also been shown to react with a CCR5/CCR2 chimera (5222) containing the amino-terminal domain of CCR5. However, this antibody does not react with CCR5 present on unfixed stimulated human PBMCs by flow cytometry. For additional information regarding epitope specificity for this antibody and other R&D Systems anti-human CCR5 antibodies, see Lee, B. et al., 1999, J. Biol. Chem. 274:9617.

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