Human CAR/NR1I3 Antibody
R&D Systems, part of Bio-Techne | Catalog # PP-N4111-00
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human, Mouse, Primate - Chlorocebus aethiops (African Green Monkey), Rabbit, Transgenic Mouse
Applications
Validated:
Immunohistochemistry, Western Blot, Immunoprecipitation
Cited:
Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry, Chromatin Immunoprecipitation (ChIP)
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # N4111
Product Specifications
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for Human CAR/NR1I3 Antibody
Application
Recommended Usage
Immunohistochemistry
Immunoprecipitation
Western Blot
Formulation, Preparation, and Storage
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: CAR/NR1I3
CAR, (MB67; NR1I3) is a 40 kDa member of the NR1 subfamily of the nuclear hormone receptor family. CAR is predominantly expressed in the liver and forms a heterodimer with RXR. The CAR/RXR heterodimer activates retinoic acid, xenobiotic and phenobarbital response elements. There are two isoforms of the CAR nuclear hormone receptor. Each contains a DNA-binding hinge and dimerization domain. One is full-length at 352 amino acids while the other shows a 4 amino acid truncation at the extreme C-terminus.
Long Name
Constitutive Androstane Receptor
Alternate Names
MB67, NR1I3
Entrez Gene IDs
9970 (Human)
Gene Symbol
NR1I3
Additional CAR/NR1I3 Products
Product Documents for Human CAR/NR1I3 Antibody
Product Specific Notices for Human CAR/NR1I3 Antibody
For research use only
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