HTRA1/PRSS11 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23869

Novus Biologicals, part of Bio-Techne
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NBP2-23869
NBP2-23869SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Bovine, Canine, Primate

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Simple Western, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all HTRA1/PRSS11 Antibodies »

Product Specifications

Immunogen

Within the range of amino acids 234-262of human HtrA1 were used as the immunogen, Gen Bank no NP_002766.1. This peptide sequence is in the serine protease domain of the HtrA1 protein.

Reactivity Notes

This antibody is reactive to Chimpanzee

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HTRA1/PRSS11 Antibody - BSA Free

Western Blot: HTRA1/PRSS11 Antibody [NBP2-23869]

Western Blot: HTRA1/PRSS11 Antibody [NBP2-23869]

Western Blot: HTRA1/PRSS11 Antibody [NBP2-23869] - Analysis of HtrA1 in human A) HeLa cell lysate (1 minute exposure) and B) human 293 cell lysate (15 minute exposure) using NBP2-23869 at 1:500.
Simple Western: HTRA1/PRSS11 Antibody [NBP2-23869]

Simple Western: HTRA1/PRSS11 Antibody [NBP2-23869]

Simple Western: HTRA1/PRSS11 Antibody [NBP2-23869] - Simple Western lane view shows a specific band for htrA1 in 0.5 mg/ml of Hek293 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

Applications for HTRA1/PRSS11 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:2000

Simple Western

1:5000

Western Blot

1:250-1: 1000
Application Notes
In Simple Western only 10 - 15 uL of the recommended dilution is used per data point.
See Simple Western Antibody Database for Simple Western validation: Tested in Hek293 lysate 0.5 mg/mL, separated by Size, antibody dilution of 1:5000, apparent MW was 67 kDa.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole sera with 50% Glycerol

Format

BSA Free

Preservative

0.025% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HTRA1/PRSS11

htrA1 encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Long Name

High Temperature Requirement Protein-1

Alternate Names

IGFBP5-protease, PRSS11

Gene Symbol

HTRA1

UniProt

Q92743

Additional HTRA1/PRSS11 Products

Product Documents for HTRA1/PRSS11 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HTRA1/PRSS11 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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